Massachusetts-based Proteostasis has entered into a worldwide collaboration with Biogen Idec to develop drugs that could treat certain neurodegenerative disorders, such as Alzheimer’s and Parkinson’s, by blocking an enzyme known as Usp14
According to Proteostasis, it will receive an initial upfront payment from Biogen (a leader in the multiple sclerosis field), along with an equity investment, and is eligible for research funding support and future development and commercial milestones that could result in total payments of up to $200 million, as well as tiered royalties.