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    1. Production

    Difco TC Yeastolate ultra-filtered (TCY UF) in scale-up optimization

    Nov. 26, 2024
    Improve titer by 50% or more with Gibco peptones

    The use of Difco™ TC Yeastolate Ultra-Filtered (TCY UF) in cell culture supplements resulted in an over 100% increase in titer yield, thereby significantly enhancing productivity in bioreactor processes. This pioneering method replaced a chemically defined CHO medium with a more effective medium and feed pairing strategy. The key findings underscore the effectiveness of TCY UF in boosting bioreactor scalability and productivity.

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